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Besides, berberine down-regulates the expression of acetylcholinesterase and inhibits acetylcholinesterase activity in Alzheimers disease model mice hippocampus which induced by heavy metals, in addition, berberine normalizes the production of inflammatory factors, such as tumor necrosis factor-alpha (TNF-), IL-6, IL-1 (Hussien et al., 2018)

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The strain can reach as high as 50 MPa and become a driving force of film deformation and ion migration at the interface 27

However, in SLE patients, especially those positive for anti-dsDNA, elevated CD8 + Tang cell levels in blood may signal endothelial damage and cardiovascular risks (71)

The most common tendons affected are the patella tendon, hamstring tendons, and the iliotibial band