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Studies with specific inhibitors of p44/42 and JNK support that the TNF-mediated increase in lipolysis is largely attributed to a reduction in perilipin levels in adipocytes (104, 105), and lower levels of perilipin have been found in adipose tissues from obese subjects (135)

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Use only sterile, single-use syringes and needles for both the addition of the diluent and the extraction of the reconstituted solution

This is important because bacteriostatic water for injection (BWFI) comes in a 30 ml multi-dose vial, which can be used over a period of 28 days after opening