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The significant increase in plasma vitamin B6 in many children with autism spectrum disorders [73, 76, 87, 92, 93] could potentially reflect diminished cellular uptake or inefficiency of cells to retain or store B6

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Competing interests The authors declare no competing interests

Expression and purification of GSTO1 for crystallization For crystallization, GSTO1 residues 1241 were cloned into an expression construct containing an N-terminal 6xHis tag followed by a tobacco etch virus (TEV) protease cleavage site and expressed in E