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Exosomal communication between cumulus-oocyte complexes and granulosa cells: a new molecular axis for oocyte competence in human-assisted Reproduction

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The OINDP classification is important because it signals that standard pharmaceutical testing protocols are insufficient nasal sprays require a specialized suite of device performance tests (spray pattern, plume geometry, droplet size distribution, dose uniformity) that are specific to this dosage form and that are detailed in dedicated FDA guidance documents