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Redox Biol Dissecting the process of human neutrophil lineage determination by using alpha-lipoic acid inducing neutrophil deficiency model

Several factors can reduce glutathione levels in the body, including: Chronic stress Poor nutrition Smoking Excessive alcohol consumption Lack of sleep Environmental pollution Aging Certain medical conditions Managing these factors may help support healthy glutathione levels over time

Elife 4 , e11682 (2015)

VanTeeffelen JW

We explained that this important result arises from the very slow change of GSH as LIMITATIONS Our models are based on the underlying physiology and the kinetics of the enzymes, but no model can encompass the entirety of biological complexity