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Inclusion Criteria Exclusion Criteria Timeline for a Trial Participant Screening Participants are screened for eligibility to participate in the trial Treatment Participants receive one of four study medicines, including CagriSema, cagrilintide, semaglutide, or placebo, with weekly injections for weight loss Follow-up Participants are monitored for safety and effectiveness after treatment Extension Participants who continue in the extension study are monitored for changes in body weight and related diseases without receiving study medicine What Are the Treatments Tested in This Trial

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Subsequent research confirmed Epitalon's ability to activate telomerase , lengthen telomeres , and delay the onset of degenerative conditions Khavinson et al., Bulletin of Experimental Biology and Medicine , 2003