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This variation in p O 2 , in particular, differentially regulates the compartmentalization and functioning of the transcription factors hypoxia-inducible factor-1 (HIF-1) and nuclear factor-B (NF-B)

ophthalmologistdiagnosed retinopathy (non-proliferative retinopathy, proliferative retinopathy or a history of laser photocoagulation), nephropathy as evidenced by microalbuminuria (30300 mcg/day), or physician-diagnosed sensory polyneuropathy (by impaired vibration, crude touch, or monofilament perception)

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Two main fluorescence techniques are key in this aspect: low molecular weight (LMW) fluorescent/fluorogenic chelating agents (probes) and genetically encoded fluorescent proteins

2024;11:e2403075