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Oxidative stress and antioxidants in hypertension - a current review

Relevant clinical trials should assess outcomes such as sleep-onset latency, total sleep time, wakefulness after sleep onset, sleep efficiency, daytime functioning and patient-reported symptoms

doi: 10.3899/jrheum.090994 149 RestrepoJFDel RinconIMolinaEBattafaranoDFEscalanteA

Although the exact mechanisms have not been discovered yet, accumulation of ROS during the active phase or day, builds up sleep pressure that is cleared during inactive phase, or night, thus, getting the body and brain ready for the prospective day

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