ZakkarMVan der HeidenKLuongLAChaudhuryHCuhlmannSHamdulaySSet alActivation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state
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Other negative health effects reported in various studies include acute poisoning and chronic conditions, including different forms of cancer (such as bladder, breast, brain, bladder, and colon cancer) (Rani et al., 2021), Parkinsons disease (Perrin et al., 2021), Alzheimers disease (Frisoni et al., 2022), infertility (Foucault et al., 2021), diabetes (Hernndez-Mariano et al., 2022), neurotoxicity (Wang et al., 2024a), and leukemia (Rafeeinia et al., 2023)
Colitis-associated cancer research: A 2016 study found that KPV reduced tumor development in a murine model of colitis-associated colon cancer, suggesting that its ability to dampen chronic gut inflammation may interrupt the inflammation-to-cancer progression that drives some colorectal cancers