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Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management

- People with poorly controlled bone-turnover conditions, until the dose-dependent osteocalcin changes seen in the 26-week rat study are better understood

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Alcohol and Ibuprofen Leads to Gastrointestinal Bleeding Ibuprofen should always be taken with food because it irritates the digestive tract