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Food and Drug Administration (FDA) classifies a product with a modified risk tobacco product (MRTP) order.[8] These provisions should be encouraged and considered at the federal level

Research has consistently demonstrated that branding on cigarette packages is targeted towards young adults and women, and may increase the appeal of smoking [68]

These surface functional groups typically consist of anionic chemical species or groups that contribute to the overall negative charge of the CQDs such as Carboxyl (COOH), Hydroxyl (-OH), and Amino (NH 2 )