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The Journal for Nurse Practitioners , 20 (8), 105157

and hence, linked with the pathogenesis of neurodegenerative disorders, including Parkinsons disease 21,22,23

In this process, LCFA must be first activated into lipoyl-CoA via acyl-CoA synthetase (ACS) (30)

Losing access to these medications would also be catastrophic for many patients with chronic illnesses such as ME/CFS, cancer, Lyme disease, anemia, multiple sclerosis, Crohns disease, and CIRS who have come to depend on these substances for quality of life and disease management

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