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There are times when symptoms get worse, known as flares, and times when there are no symptoms, known as remission

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Purification is typically performed using high-performance liquid chromatography, and analytical verification methods such as mass spectrometry are used to confirm peptide identity

360 , 441 , 444 , 448 , 456 , 457 Such findings are promising and suggest that identifying and reducing risk factors for dementia may be effectivewhether interventions occur person by person (such as obtaining treatment for one's blood pressure) or are integrated into the fabric of communities (such as changes in education policies)