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Nicotine and other psychoactive compounds with antidepressant properties in tobacco smoke, which act as monoamine oxidase inhibitors in the brain, can alter mood and have a calming effect, depending on dose

Martin Dockrell, the Tobacco Control Lead for Public Health England, disagrees: The data that shows that vaping is an effective way to quit was reviewed in Vaping in England: an evidence update including vaping for smoking cessation, February 2021. Three systematic reviews consistently found vaping products containing nicotine were significantly more effective for helping people stop smoking than NRT

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Taken together, TSPO measurement levels with PET scanning can be used as a marker for neuroinflammation levels

There are signs that rules on e-cigarettes in the UK could be relaxed further