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Oxygen tension in cell culture incubators (138 mmHg) is higher than in arterial blood (80100 mmHg) and markedly higher than in tumor hypoxia, where oxygen tension can decrease below 15 mmHg [38]

[55] have suggested that the relative stability of methionine is due to the complicated kinetics of MAT-I and MAT-III and we have confirmed this by model experiments [56]