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NNMT sits between NAD+ metabolism and one-carbon methylation metabolism, pathways that support redox reactions, DNA repair, and transcriptional regulation

Protects Against Environmental Damage: Daily exposure to UV rays, pollution, and blue light can weaken skin cells

Bose P, Masarova L, Pemmaraju N, Bledsoe SD, Daver N, Jabbour EJ, Kadia TM, Estrov ZE, Kornblau SM , Andreeff M, Cortes JE, Borthakur, G Alvarado Y, Huynh-Lu J, Nguyen-Cao MM, Richie MA, Dobbins MH, McCrackin SA, Zhou L, Pierce SA, Wang X, Allison M Pike AM, Garcia-Manero G, Kantarjian H, Verstovsek S

Because AMPK is relevant in all tissues, this makes metformin extremely important in reducing metabolic imbalances in the entire body

Wong, H