This likely accommodates the essential role of Egr1 indirectly controlling the expression of other genes, and thereby, neural activity, neural plasticity, and learning (Knapska & Kaczmarek, 2004), similar to the implied role of Egr1 gene in inflammation, myocardial injury (Rayner et al., 2013), brain injuries following transient focal ischemia (Tureyen, Brooks, Bowen, Svaren, & Vemuganti, 2008) or permanent occlusion of the middle cerebral artery (Beck, Semisch, Culmsee, Plesnila, & Hatzopoulos, 2008)
Trials so far are small and sometimes inconclusive, and the ideal dose, schedule, and stacking approach remain open questions
There is insufficient clinical trial data to confirm their efficacy and safety in humans
Anything with 40 or more amino acids is classified as a biologic, which requires a biologics license to compound
Fungal and bacterial microbiome dysbiosis and imbalance of trans-kingdom network in asthma