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Blood 117 , 54385448 (2011)

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

c-fos gene expression has been identified to be significantly lower in leiomyoma cells as compared to normal myometrium which is consistent with the previous study that has suggested that a decrease in the smooth muscle cells progenitors could have contributed to the formation of UF ( c-fos expression in leiomyoma cells induced by SB is associated with its antiproliferative actions (Lee et al., 2004a)

Diarrhea: Loose stools, which can happen if the body is trying to quickly eliminate excess material

Although not the focus of phase I/II trials, patients treated with ADI-PEG20 did not show any reduction in the melanoma progression and whether the treatment may prolong survival seems to depend on the disease stages during treatment [140, 141]