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Zhou W, Barkow JC, Freed CR

Additionally, the deletion of gliT leads to the abrogation of the secretion of gliotoxin and renders the A

SULT1E1 is the major SULT for estrogen sulfation [328,329], while SULT1A1 and SULT1A3 also sulfate estrogens, but with a lower affinity [327]

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It is worth noting that, different from VKOR that reduces vitamin K by the active site free cysteines (Cys132 and Cys135) which are oxidized to a disulfide after vitamin K reduction 21,55 , FSP1 does not have active site residues that are directly involved in vitamin K reduction