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In accordance with this, pathway analysis of the RNA transcriptome identified oestrogen-mediated S-phase entry, p53 signalling and G1/S checkpoint regulation as canonical pathways significantly modulated in response to GSTO1 knockdown (Supplementary Fig

Our inability to precisely identify both the molecular mechanism and the relevant cell type(s) that mediate this phenotype are a weakness of this study, and future work should aim to address this in greater detail using in situ immunohistochemistry and single-cell sequencing

Treatment of hypertension and diabetes mellitus in patients with chronic kidney disease: a review

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Merck KGaA) supplemented with 0.1% PEST