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Therefore, serum potassium levels and the platelet count should be monitored carefully during therapy

One retrospective observational study conducted in Japan has suggested that the early administration of this compound was associated with better functional outcomes and reduce HT after AIS (245), although there is data suggesting that the use of this compound may be related to increased HT (246)

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Patients with visceral hypersensitivity tend to have lower colonic distension pain threshold where a normal stimulus will intensify the pain in the patients (Camilleri et al., 2001)