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In addition, APAP cases that did not develop liver injury, as well as patients who are receiving APAP at therapeutic doses are important controls that should be included in future clinical studies

It is essential for the creation of red blood cells, DNA synthesis, and the maintenance of the nervous system

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Current protocols recommend treating patients with an initial dose of 150 mg/kg NAC, infused over a period of an hour, upon hospitalization, followed by decreasing amounts of NAC infused over the next 20 hours

Footnotes Edited by: Ling Wang, Dalian Medical University, China Reviewed by: Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation