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While this effect appears to be related to the magnitude and rapidity of glucose lowering rather than a direct effect of the medication itself, patients with a history of diabetic retinopathy should undergo careful ophthalmologic evaluation before and during treatment, and the potential risks should be weighed against the expected benefits of improved glycemic control

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This study offers valuable insights into the mechanisms underlying persistent VCD associated with long COVID and highlights the therapeutic potential of vitamin B12 as an epidrug to prevent or mitigate this impairment

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