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MECHANISM CATEGORIES RESEARCH CONDITIONS SAFETY Side effects Limited human safety data Animal toxicology shows wide therapeutic window Injection-site reactions reported anecdotally Known interactions Anticoagulants (theoretical, due to angiogenic activity unstudied) Contraindications Active malignancy (theoretical, due to angiogenic mechanism) Pregnancy/lactation (unstudied) REGULATORY STATUS FDA Placed on FDA Category 2 of the 503A bulks list (September 2023 update), barring compounding pharmacies from preparing it under section 503A
doi: 10.1016/s0928-4257(99)00123-0
Combining the two molecules yielded better results than either molecule alone, though the side effects from the combo were higher
Furthermore, the 0.9% benzyl alcohol preservative inhibits microbial growth, allowing multi-dose use of reconstituted peptide solutions without compromising sterility
I have never heard of a single patient who came to harm from having a single loading dose of B12
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