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Patients were subdivided by whether they received surgery alone or adjuvant 5FU-based chemotherapy and subsequently grouped based on the median overall survival into either good outcome or poor outcome

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Furthermore, SCFAs upregulate the expression of Foxp3, a key transcription factor for regulatory T cells, through HDAC inhibition (208, 209), promoting Treg differentiation and suppressing the production of pro-inflammatory cytokines (210)

More recently, two step-by-step protocols have been published to improve reproducibility of eryptosis experiments (Jema et al., 2017

TREK-1 blockade increases neuronal excita