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[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Mishra R., Haldar S., Placencio V., Madhav A., Rohena-Rivera K., Agarwal P., Duong F., Angara B., Tripathi M., Liu Z., et al

A3: Yes

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(A) Intrinsic resistance mechanisms: While mutant KRAS is essential for tumorigenesis, tumor cells can acquire KRAS independence during proliferation through processes such as epithelial-mesenchymal transition (EMT), YAP activation, or metabolic reprogramming

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