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* Correspondence: Monica Barne, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Regardless, once formed, a protein sulfenate would rapidly react with GSH to produce the mixed disulfide, and this could be the mechanism through which PSSG formed for some proteins in the cytosol during oxidative stress when H 2 O 2 is high enough to overcome a slow rate constant

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Table 1 Data presented are SOFA scores (numbers are in mean standard)

On the other hand, in the group receiving MTX plus ROF, there was marked preservation of normal histological features of hepatic tissue