FDA staff's own briefing document, posted publicly ahead of the meeting as part of the docket, proposes that TB-500 (free base) and TB-500 acetate not be added to the list, citing incomplete physicochemical characterization, a lack of evidence of effectiveness for wound healing (including an in-vitro fibroblast study in which TB-500 reportedly did not induce wound healing), and insufficient nonclinical and clinical safety data
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Better Focus Improve your focus and mental clarity with regular B12 injections
Lung cancer mortality among nonsmoking uranium miners exposed to radon daughters
Providing only one form still supports all B12-dependent processes in individuals with normal conversion capacity