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The bottom line: any tobacco use carries risk, and hand-rolling doesn't change that fundamental reality

The product has the potential to be contaminated during each step of the process, including cultivation

Adolescent cigarette smoking has been falling for many years, but the decline in e-cigarette and hookah use was more remarkable

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Product allocation could not be blinded, which could affect results if nicotine replacement was seen as an inferior option and those participants were putting less effort into their quit attempt