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The observation that DNA methylation can account for rather more of the variance in serum UA than genetic polymorphisms 32 indicates the strong potential of investigation into this and other epigenetic factors in relation to risk of PD and, of course, other disorders associated with UA

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Int J Mol Sci 23

In addition, in vitamin E group a significant increase in the vitamin E concentration and the antioxidant capacity of lipophilic antioxidants was found, but not the total antioxidant capacity compared to placebo [36]

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