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Research confirms that high-dose progesterone upregulates Ki67 mRNA expression [37] and synergistically enhances the expression of proliferating cell nuclear antigen (PCNA), epidermal growth factor (EGF), and epidermal growth factor receptor (EGFR) with E 2 , thereby enhancing the proliferative potential of fibroid cells [38]

USA 106 , 83508355 (2009)

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