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Description

A GH pulse from the pituitary travels to the liver and peripheral tissues, where it drives the production of IGF-1 (insulin-like growth factor 1), the mediator responsible for most of GHs anabolic and recovery-related effects

Similar storage considerations apply to newer compounds like retatrutide and cagrilintide

An additional very welcome benefit of low IGF-1 may also be lower cancer risk

Sermorelin is often considered the closest to natural HGH signaling because it stimulates the body to produce and release its own growth hormone rather than replacing it