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44, Nov

10.1016/j.jcis.2004.02.012

Free Radicals in Biology and Medicine

4.4.3 Homocysteine and DKD vascular injury Homocysteine (Hcy) is an intermediate metabolite formed during the conversion of methionine to cysteine, and elevated plasma levels (hyperhomocysteinemia, HHcy) are closely associated with increased cardiovascular disease risk (145)