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Kim HC, Shin EJ, Jang CG, Lee MK, Eun JS, et al

Using a genome-wide screen, we identify aldolase A, a key glycolytic enzyme that converts fructose-1,6-bisphosphate (FBP), as a regulatory switch that links metabolic flux to FA assembly and cell morphogenesis

This research was funded by the Natural Science Foundation of Chongqing (CSTB2023NSCQ-MSX1081) and the National Natural Science Foundation of China (82304032)

First, 72 percent of participants who entered the trial with prediabetes reverted to normoglycemia by week 68

High dose oral cobalamin may be a suitable alternative in selective cases, where intramuscular injections are not tolerated and compliance is not a problem