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This allows the carotenoids to produce chemicals that help create the sweeter fragrance and flavor aspects of the cigar

Appl Microbiol Biotechnol

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We propose that cigarette smoking impairs immunosuppressive function of Tregs by reducing the number of suppressive Tregs or increasing the prevalence of non-suppressive Tregs, leading to an enhanced autoimmune component in COPD pathogenesis, while increased Treg numbers may occur in some smokers under circumstances, leading to worsened respiratory infections