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PLoS ONE 9 , e97503 (2014)

It's what your body actually usesunlike cyanocobalamin, which must be converted and may be less effective, especially for those with MTHFR mutations

When stratified by administration route, the mean percentage changes were: Intramuscular (IM): 307% Oral: 285% Sublingual: 199% IM administration showed the highest average B12 increase, although oral and sublingual routes also yielded substantial improvements, supporting their use as effective and less invasive alternatives

Vitamin B12 Fact Sheet for Health Professionals