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doi: 10.3389/fimmu.2022.816282 43 RochetteLDogonGRigalEZellerMCottinYVergelyC

This broad spectrum of manifestations reflects the complexity of its pathophysiology, which involves a combination of dopaminergic neuron loss, oxidative stress, alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, neuroinflammation, and disruptions in the gut-brain axis 5,6,7,8,9

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