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Elevated ROS levels in OA synovium have been confirmed experimentally, where mean fluorescence intensity of ROS is markedly higher than in healthy controls, indicative of pronounced oxidative stress in OA joints (149)

It comprises three anatomical layers: the uveal-TM, corneoscleral-TM, and juxtacanalicular, also known as the cribriform-TM [414]

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The mode of action and use of chlorothiazide and related compounds

Taken together, these findings suggest that glutathione has an important role in acetaldehyde tolerance, as a direct scavenger of acetaldehyde in the cell