In vitro studies have shown that certain flavonoids, at high concentrations, can inhibit the growth of probiotic bacteria such as Lactobacillus app., while promoting the proliferation of opportunistic pathogens and inducing the accumulation of harmful metabolites, including H 2 S and NH 3 (Pan et al., 2023), which may adversely affect gut microbial homeostasis under specific conditions
In cirrhosis patients, specific patterns of gut flora dysbiosis are associated with adverse clinical outcomes
The study was approved by the Animal Experimentation Ethics Committees of University of Campinas (CEUA/UNIMCAP, protocol 4557-1(A)/2018)
Agency for Healthcare Research and Quality (US)
So far, in 2017, three statesUtah, Washington, and Hawaiiattempted to lower their states legal BAC limit from .08% to .05% BAC