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Bioavailability of nicotine from ST products is dependent on the pH of the product, since unprotonated nicotine (in more alkaline products) is absorbed more efficiently and more rapidly across the mucous membranes of the mouth than protonated forms of the drug from more acidic products

State health experts have blamed flavored vapes for the prevalence of their use among high school-aged students

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13 There is some uncertainty which species of Nicotiana was first brought to Europe

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