The production of ACPA is influenced by several factors, including genetics (specifically genes encoding HLA-DR/SEs/Shared epitopes), environmental elements, smoking habits, the presence of lymphoid-specific protein tyrosine phosphatase non-receptor type-22 (PTPN22), and certain infectious agents such as Porphyromonas gingivalis, Aggregatibacter Actinomycetemcomitans, and the Epstein-Barr virus
Antioxid (Basel Switzerland)
Ulcerative colitis: recent advances in the understanding of disease pathogenesis
It is the most common type of cancer in children, accounting for one quarter of all childhood cancer cases (7)
Nerve Block-Assisted Intradermal Injection of Tranexamic Acid, Vitamin C, and Glutathione for Melasma: A Split-Face Comparative Study