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When stratified by administration route, the average percentage reductions were: Intramuscular (IM): 48.3% Sublingual: 30.7% Oral: 30.3% These results suggest that IM administration leads the most pronounced homocysteine reduction, however, sublingual and oral routes also demonstrate clinically relevant effects

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However, as research continued, experts found that GHK could modulate a number of different cells besides those in the liver.4 GHK is naturally found in human saliva, plasma, and urine, but its standard levels are reduced by over half once you reach age 60