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Considering that nicotine gum chewing does not yield any acute change in LV diastolic performance in young healthy individuals [30], it is likely that the acute effect of smoking on LV diastolic function may not be due to nicotine alone

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Clinical and Experimental Optometry, 2012

In low-grade and machine-made cigars, chopped tobacco leaves are used for the filler, and long leaves or a type of "paper" made from reconstituted tobacco pulp is used for the wrapper

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