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That is a substantial rate for a side effect that neither semaglutide nor tirzepatide produces at any meaningful frequency

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Reactive Oxygen Species (ROS) are increased by the consumption of sugars and oxidized vegetable oils, smoking, alcohol, exposure to environmental toxins, high or chronic emotional stress, circadian rhythm dysregulation (poor sleep), lack of exercise, infections, and a lack of antioxidant intake

J Neurosci 23 : 55035506