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*Corresponding Author: Nasser Mikhail, Endocrinology Division, Department of Medicine2, Olive View-UCLA Medical Center, David-Geffen UCLA Medical School, CA, USA

Real-time quantitative PCR Total RNA was extracted from aortic tissue and endothelial cells using TRIzol reagent (Takara Bio Inc., 9108), following the manufacturers instructions

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The GLP-1 and GIP receptors play essential roles in augmenting insulin secretion and glucose homeostasis, whereas GCG receptor engagement elevates circulating GCG levels, promoting catabolic processes