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Odd-chain fatty acids as a biomarker for dietary fiber intake: a novel pathway for endogenous production from propionate

Mechanistic studies indicate that scorpion venom fibrinolytic peptides upregulate prostacyclin (6-keto-PGF1 ) and nitric oxide (NO) levels while modulating the activity of plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (tPA)

This drug is widely used as an antifibrinolytic agent and has been found to inhibit plasminogenkeratinocyte interaction leading to decrease in activity of tyrosinase, thereby resulting in decreased synthesis of melanin from the melanocytes.[] Human keratinocytes secrete the urokinase-type plasminogen activator, which increases the activity of melanocytes leading to increased synthesis of melanin and the blockade of this effect may be the mechanism behind therapeutic effect of TA for the treatment of melasma.[] Glutathione is an anti-oxidant tri-peptide, which is normally present in humans and has also been tried successfully as a treatment modality for melasma

Headache 41:171177 Wanic-Kossowska M (1997) Protective role of carnitine in acetate metabolism of patients with uremia treated by hemodialysis

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