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On March 5, 2025, the Drug Enforcement and Policy Center hosted a webinar featuring experts discussing the national and Ohio landscape for intoxicating hemp regulation

The researchers concluded that synthetic cannabinoids are associated with "more severe and persistent psychotic symptoms and emotional dysregulation compared to natural cannabis." "These findings underscore the need for targeted interventions addressing emotional regulation and salience processing in cannabis-related psychosis," the authors wrote

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An erratic limbic system manifests as disturbances in mood, including anxiety, depression, and irritability