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Timing is critical, so if you have excess B12 levels, get checked

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After for 4 weeks inducation, we found the thyroids were significantly enlarged in the hypothyroidism (hypo) group, while H&E staining showed that the volume of thyroids follicles were significantly smaller than that in the control group, and the colloid in the follicular cavities were reduced (Figure 1A), while the body weight of the hypo group were significantly lower than that of the control group and showed a decreasing trend starting from the third week (Figure 1B)