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For severe cases, the first dose is usually 1,000 mcg given intramuscularly every day or every other day for a week or two

Several HDACi are now in Phase I and Phase II clinical trials for cancer therapeutics (Marks and Xu, 2009)

histologically, they appear as distended, weakly-staining cells with large, realtively clear nuclei) and brain edema were described and evaluated semiquantitatively (22)

they are psychologically inaccessible