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Adjunctive low-dose docosahexaenoic acid (DHA) for major depression: an open-label pilot trial

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some microbially modified bile acids (like iso-deoxycholic acid) can cross into the brain and have been shown to modulate microglial activity and cholesterol metabolism in neurons [80]

Chin Med J 123(2):165172 Lu B, Driban JB, Xu C, Lapane KL, McAlindon TE, Eaton CB (2017) Dietary fat intake and radiographic progression of knee osteoarthritis: data from the osteoarthritis initiative

Breaking this cycle requires a targeted intervention to restore antioxidant capacity and safely bind and remove accumulated toxins